Carnivore protoparvovirus 1 is a species of parvovirus that infects carnivorans. It causes a highly contagious disease in both dogs and cats separately. The disease is generally divided into two major genogroups: FPV containing the classical feline panleukopenia virus (FPLV), and CPV-2 containing the canine parvovirus type 2 (CPV-2) which appeared in the 1970s.

FPLV is known to infect all wild and domestic members of the felid (cat) family worldwide. It is a highly contagious, severe infection that causes gastrointestinal, immune system, and nervous system disease. Its primary effect is to decrease the number of white blood cells, causing the disease known as feline panleukopenia.

Although it was once thought that only FPLV infects cats, it has been confirmed that a feline panleukopenia illness can be caused by CPV 2a, 2b, and 2c.

FPLV is commonly referred to as:

• feline infectious enteritis virus (FIE)
• feline parvovirus (FPV or FP or "feline parvo")
• feline parvoviral enteritis

It is sometimes confusingly referred to as "cat plague" and "feline distemper".

In addition to members of the felid family, it can also affect other carnivorans (e.g. raccoon, mink).